STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUS1Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (103 aa)    
Predicted Functional Partners:
A0A1Y1Z3I7
Bromo domain-containing protein.
    
 0.997
A0A1Y1Z9F7
SCA7-domain-containing protein.
    
 0.996
A0A1Y1XXF9
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.992
A0A1Y1ZC62
SAGA-associated factor 11.
    
 0.992
A0A1Y1Z951
Transcription initiation factor TFIID subunit 6.
    
 0.991
A0A1Y1YFP2
Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
    
 0.989
A0A1Y1Z0H5
Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]
   
 0.989
A0A1Y1XM35
Putative histone acetyltransferase.
    
 0.986
A0A1Y1XTX0
TFIID-31kDa-domain-containing protein.
   
 0.986
A0A1Y1WQH6
DUF1325-domain-containing protein.
   
 0.985
Your Current Organism:
Basidiobolus meristosporus
NCBI taxonomy Id: 1314790
Other names: B. meristosporus CBS 931.73, Basidiobolus meristosporus CBS 931.73
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.