A0A1Y1YIH8 protein (Basidiobolus meristosporus)

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second shell of interactors

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Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

A0A1Y1YIH8

Antiviral helicase. (1061 aa)

Predicted Functional Partners:

A0A1Y1Y5N2

0.994

K493DRAFT_6091

0.994

K493DRAFT_1293

0.990

A0A1Y1YUC6

0.990

A0A1Y1XWY3

0.989

A0A1Y1YXZ2

0.989

A0A1Y1Y7V7

0.988

A0A1Y1XXB3

0.987

A0A1Y1Y603

0.987

A0A1Y1Y7S7

0.987

Your Current Organism:

Basidiobolus meristosporus

NCBI taxonomy Id: 1314790
Other names: B. meristosporus CBS 931.73, Basidiobolus meristosporus CBS 931.73

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1Y1XWY3	A0A1Y1XXB3	A0A1Y1XWY3	A0A1Y1XXB3	Bystin-domain-containing protein.	Nucleic acid-binding protein.	0.995
A0A1Y1XWY3	A0A1Y1Y5N2	A0A1Y1XWY3	A0A1Y1Y5N2	Bystin-domain-containing protein.	Utp12-domain-containing protein.	0.999
A0A1Y1XWY3	A0A1Y1Y603	A0A1Y1XWY3	A0A1Y1Y603	Bystin-domain-containing protein.	Nucleic acid-binding protein.	0.995
A0A1Y1XWY3	A0A1Y1Y7S7	A0A1Y1XWY3	A0A1Y1Y7S7	Bystin-domain-containing protein.	WD40 repeat-like protein.	0.997
A0A1Y1XWY3	A0A1Y1Y7V7	A0A1Y1XWY3	A0A1Y1Y7V7	Bystin-domain-containing protein.	Uncharacterized protein.	0.928
A0A1Y1XWY3	A0A1Y1YIH8	A0A1Y1XWY3	A0A1Y1YIH8	Bystin-domain-containing protein.	Antiviral helicase.	0.989
A0A1Y1XWY3	A0A1Y1YUC6	A0A1Y1XWY3	A0A1Y1YUC6	Bystin-domain-containing protein.	DUF663-domain-containing protein.	0.999
A0A1Y1XWY3	A0A1Y1YXZ2	A0A1Y1XWY3	A0A1Y1YXZ2	Bystin-domain-containing protein.	Uncharacterized protein.	0.914
A0A1Y1XWY3	K493DRAFT_1293	A0A1Y1XWY3	A0A1Y1YMM0	Bystin-domain-containing protein.	WD repeat protein.	0.999
A0A1Y1XWY3	K493DRAFT_6091	A0A1Y1XWY3	A0A1Y1YL80	Bystin-domain-containing protein.	Small-subunit processome.	0.997
A0A1Y1XXB3	A0A1Y1XWY3	A0A1Y1XXB3	A0A1Y1XWY3	Nucleic acid-binding protein.	Bystin-domain-containing protein.	0.995
A0A1Y1XXB3	A0A1Y1Y5N2	A0A1Y1XXB3	A0A1Y1Y5N2	Nucleic acid-binding protein.	Utp12-domain-containing protein.	0.988
A0A1Y1XXB3	A0A1Y1Y7S7	A0A1Y1XXB3	A0A1Y1Y7S7	Nucleic acid-binding protein.	WD40 repeat-like protein.	0.988
A0A1Y1XXB3	A0A1Y1Y7V7	A0A1Y1XXB3	A0A1Y1Y7V7	Nucleic acid-binding protein.	Uncharacterized protein.	0.962
A0A1Y1XXB3	A0A1Y1YIH8	A0A1Y1XXB3	A0A1Y1YIH8	Nucleic acid-binding protein.	Antiviral helicase.	0.987
A0A1Y1XXB3	A0A1Y1YUC6	A0A1Y1XXB3	A0A1Y1YUC6	Nucleic acid-binding protein.	DUF663-domain-containing protein.	0.995
A0A1Y1XXB3	A0A1Y1YXZ2	A0A1Y1XXB3	A0A1Y1YXZ2	Nucleic acid-binding protein.	Uncharacterized protein.	0.914
A0A1Y1XXB3	K493DRAFT_1293	A0A1Y1XXB3	A0A1Y1YMM0	Nucleic acid-binding protein.	WD repeat protein.	0.995
A0A1Y1XXB3	K493DRAFT_6091	A0A1Y1XXB3	A0A1Y1YL80	Nucleic acid-binding protein.	Small-subunit processome.	0.997
A0A1Y1Y5N2	A0A1Y1XWY3	A0A1Y1Y5N2	A0A1Y1XWY3	Utp12-domain-containing protein.	Bystin-domain-containing protein.	0.999

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Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.909

expected number of edges:

23

PPI enrichment p-value:

0.00171

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006366

Transcription by RNA polymerase II

5 of 77

1.6

1.53

0.00030

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005665

RNA polymerase II, core complex

4 of 12

2.31

2.73

4.99e-06

GO:0005847

mRNA cleavage and polyadenylation specificity factor complex

2 of 13

1.98

0.89

0.0206

GO:0005736

RNA polymerase I complex

2 of 13

1.98

0.89

0.0206

GO:0005666

RNA polymerase III complex

2 of 16

1.89

0.84

0.0245

GO:0140513

Nuclear protein-containing complex

6 of 537

0.84

0.58

0.0088

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1686

RNA polymerase II, core complex

4 of 12

2.31

2.65

7.49e-06

CL:1974

mRNA cleavage and polyadenylation specificity factor complex

2 of 10

2.09

0.86

0.0251

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

4 of 38

1.81

1.95

5.61e-05

map03015

mRNA surveillance pathway

3 of 81

1.36

0.77

0.0196

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-77075

RNA Pol II CTD phosphorylation and interaction with CE

4 of 27

1.96

1.95

0.00010

MAP-72086

mRNA Capping

4 of 29

1.93

1.94

0.00010

MAP-113418

Formation of the Early Elongation Complex

4 of 29

1.93

1.94

0.00010

MAP-9018519

Estrogen-dependent gene expression

4 of 31

1.9

1.92

0.00010

MAP-75955

RNA Polymerase II Transcription Elongation

4 of 36

1.84

1.87

0.00010

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

4 of 73

1.53

1.08

0.0042

GOCC:0005736

RNA polymerase I complex

2 of 7

2.25

0.93

0.0190

GOCC:0005665

RNA polymerase II, core complex

2 of 8

2.19

0.93

0.0190

GOCC:0005847

mRNA cleavage and polyadenylation specificity factor complex

2 of 11

2.05

0.87

0.0234

GOCC:0055029

Nuclear DNA-directed RNA polymerase complex

3 of 55

1.53

0.82

0.0190

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 15

2.09

1.69

0.00052

KW-0349

Heme

2 of 23

1.73

0.68

0.0483

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036866

Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

3 of 12

2.19

1.34

0.0030

IPR022712

Beta-Casp domain

2 of 2

2.79

1.0

0.0153

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01027

Beta-Casp domain

2 of 2

2.79

1.33

0.0038

SM01117

Cytochrome b5-like Heme/Steroid binding domain

2 of 16

1.89

0.7

0.0473

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