A0A1Y1YIL4 protein (Basidiobolus meristosporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A1Y1YIL4

6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (485 aa)

Predicted Functional Partners:

A0A1Y1XVE3

0.977

A0A1Y1XW24

0.976

A0A1Y1Z5C8

0.976

A0A1Y1YR45

0.925

A0A1Y1YST4

0.925

A0A1Y1Z982

0.849

A0A1Y1ZCU3

0.849

A0A1Y1XX14

0.823

A0A1Y1XS72

0.814

A0A1Y1ZC28

0.814

Your Current Organism:

Basidiobolus meristosporus

NCBI taxonomy Id: 1314790
Other names: B. meristosporus CBS 931.73, Basidiobolus meristosporus CBS 931.73

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1Y1XS72	A0A1Y1XVE3	Actin-like ATPase domain-containing protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.445
A0A1Y1XS72	A0A1Y1XW24	Actin-like ATPase domain-containing protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.445
A0A1Y1XS72	A0A1Y1XX14	Actin-like ATPase domain-containing protein.	Dihydroxy-acid dehydratase.	0.866
A0A1Y1XS72	A0A1Y1YIL4	Actin-like ATPase domain-containing protein.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.814
A0A1Y1XS72	A0A1Y1YR45	Actin-like ATPase domain-containing protein.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.720
A0A1Y1XS72	A0A1Y1YST4	Actin-like ATPase domain-containing protein.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.720
A0A1Y1XS72	A0A1Y1Z5C8	Actin-like ATPase domain-containing protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.445
A0A1Y1XS72	A0A1Y1Z982	Actin-like ATPase domain-containing protein.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.889
A0A1Y1XS72	A0A1Y1ZC28	Actin-like ATPase domain-containing protein.	Ribose/galactose isomerase.	0.871
A0A1Y1XS72	A0A1Y1ZCU3	Actin-like ATPase domain-containing protein.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.889
A0A1Y1XVE3	A0A1Y1XS72	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Actin-like ATPase domain-containing protein.	0.445
A0A1Y1XVE3	A0A1Y1XX14	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Dihydroxy-acid dehydratase.	0.938
A0A1Y1XVE3	A0A1Y1YIL4	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.977
A0A1Y1XVE3	A0A1Y1YR45	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.908
A0A1Y1XVE3	A0A1Y1YST4	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.908
A0A1Y1XVE3	A0A1Y1Z982	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.668
A0A1Y1XVE3	A0A1Y1ZC28	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Ribose/galactose isomerase.	0.461
A0A1Y1XVE3	A0A1Y1ZCU3	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.668
A0A1Y1XW24	A0A1Y1XS72	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Actin-like ATPase domain-containing protein.	0.445
A0A1Y1XW24	A0A1Y1XX14	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Dihydroxy-acid dehydratase.	0.938

page 1 of 5

Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006620

Post-translational protein targeting to endoplasmic reticulum membrane

7 of 15

2.83

7.49

4.25e-15

GO:0031204

Post-translational protein targeting to membrane, translocation

6 of 8

3.03

6.94

1.18e-13

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

3 of 12

2.56

1.62e-05

GO:0008104

Protein localization

8 of 496

1.37

2.02

3.55e-08

GO:0006616

SRP-dependent cotranslational protein targeting to membrane, translocation

2 of 4

2.86

1.69

0.00084

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008320

Protein transmembrane transporter activity

5 of 16

2.65

4.58

1.87e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030867

Rough endoplasmic reticulum membrane

6 of 10

2.94

6.83

1.45e-13

GO:0140534

Endoplasmic reticulum protein-containing complex

6 of 83

2.02

3.73

3.43e-09

GO:0071256

Translocon complex

3 of 3

3.16

3.45

5.32e-07

GO:0031207

Sec62/Sec63 complex

3 of 5

2.94

3.21

1.32e-06

GO:0005789

Endoplasmic reticulum membrane

7 of 347

1.46

2.14

1.73e-07

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:19150

Post-translational protein targeting to membrane, translocation

6 of 6

3.16

7.39

2.25e-14

CL:19146

Rough endoplasmic reticulum, and Signal peptidase complex

7 of 17

2.77

7.38

5.33e-15

CL:4562

Nucleotide-activated protein kinase complex, and Energy dependent regulation of mTOR by LKB1-AMPK

2 of 13

2.34

1.02

0.0132

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03060

Protein export

5 of 34

2.32

4.11

4.88e-09

map04141

Protein processing in endoplasmic reticulum

5 of 270

1.43

1.57

4.97e-05

map04145

Phagosome

3 of 73

1.77

1.46

0.00087

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-380972

Energy dependent regulation of mTOR by LKB1-AMPK

3 of 17

2.4

1.9

0.00027

MAP-165159

MTOR signalling

3 of 28

2.19

1.71

0.00053

MAP-9609523

Insertion of tail-anchored proteins into the endoplasmic reticulum membrane

2 of 13

2.34

1.0

0.0147

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030867

Rough endoplasmic reticulum membrane

6 of 14

2.79

6.34

8.28e-13

GOCC:0005789

Endoplasmic reticulum membrane

7 of 154

1.82

3.45

1.06e-09

GOCC:0071256

Translocon complex

3 of 3

3.16

3.38

7.20e-07

GOCC:0031207

Sec62/Sec63 complex

3 of 5

2.94

3.14

1.76e-06

GOCC:0005783

Endoplasmic reticulum

7 of 320

1.5

2.28

7.82e-08

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About