A0A1Y1YP66 protein (Basidiobolus meristosporus)

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Known Interactions

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Predicted Interactions

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gene fusions

gene co-occurrence

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Score

A0A1Y1YP66

FAD/NAD(P)-binding domain-containing protein. (405 aa)

Predicted Functional Partners:

BNA5

0.780

A0A1Y1YEY0

0.754

A0A1Y1Z294

0.754

A0A1Y1YVF2

0.736

A0A1Y1X1G2

0.706

A0A1Y1X6L1

0.706

A0A1Y1Y2W4

0.691

A0A1Y1Z8K7

0.691

A0A1Y1YDX8

0.688

A0A1Y1WQ40

0.671

Your Current Organism:

Basidiobolus meristosporus

NCBI taxonomy Id: 1314790
Other names: B. meristosporus CBS 931.73, Basidiobolus meristosporus CBS 931.73

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1Y1WQ40	A0A1Y1YP66	A0A1Y1WQ40	A0A1Y1YP66	S-adenosyl-L-methionine-dependent methyltransferase.	FAD/NAD(P)-binding domain-containing protein.	0.671
A0A1Y1X1G2	A0A1Y1X6L1	A0A1Y1X1G2	A0A1Y1X6L1	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.738
A0A1Y1X1G2	A0A1Y1YDX8	A0A1Y1X1G2	A0A1Y1YDX8	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.628
A0A1Y1X1G2	A0A1Y1YEY0	A0A1Y1X1G2	A0A1Y1YEY0	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Tryptophan synthase.	0.502
A0A1Y1X1G2	A0A1Y1YP66	A0A1Y1X1G2	A0A1Y1YP66	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	FAD/NAD(P)-binding domain-containing protein.	0.706
A0A1Y1X1G2	A0A1Y1YVF2	A0A1Y1X1G2	A0A1Y1YVF2	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	HAD-superfamily hydrolase.	0.751
A0A1Y1X1G2	A0A1Y1Z294	A0A1Y1X1G2	A0A1Y1Z294	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Tryptophan synthase.	0.502
A0A1Y1X6L1	A0A1Y1X1G2	A0A1Y1X6L1	A0A1Y1X1G2	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.738
A0A1Y1X6L1	A0A1Y1YDX8	A0A1Y1X6L1	A0A1Y1YDX8	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.628
A0A1Y1X6L1	A0A1Y1YEY0	A0A1Y1X6L1	A0A1Y1YEY0	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Tryptophan synthase.	0.502
A0A1Y1X6L1	A0A1Y1YP66	A0A1Y1X6L1	A0A1Y1YP66	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	FAD/NAD(P)-binding domain-containing protein.	0.706
A0A1Y1X6L1	A0A1Y1YVF2	A0A1Y1X6L1	A0A1Y1YVF2	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	HAD-superfamily hydrolase.	0.751
A0A1Y1X6L1	A0A1Y1Z294	A0A1Y1X6L1	A0A1Y1Z294	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Tryptophan synthase.	0.502
A0A1Y1Y2W4	A0A1Y1YDX8	A0A1Y1Y2W4	A0A1Y1YDX8	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.834
A0A1Y1Y2W4	A0A1Y1YP66	A0A1Y1Y2W4	A0A1Y1YP66	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	FAD/NAD(P)-binding domain-containing protein.	0.691
A0A1Y1YDX8	A0A1Y1X1G2	A0A1Y1YDX8	A0A1Y1X1G2	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.628
A0A1Y1YDX8	A0A1Y1X6L1	A0A1Y1YDX8	A0A1Y1X6L1	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.628
A0A1Y1YDX8	A0A1Y1Y2W4	A0A1Y1YDX8	A0A1Y1Y2W4	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.834
A0A1Y1YDX8	A0A1Y1YEY0	A0A1Y1YDX8	A0A1Y1YEY0	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	Tryptophan synthase.	0.852
A0A1Y1YDX8	A0A1Y1YP66	A0A1Y1YDX8	A0A1Y1YP66	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	FAD/NAD(P)-binding domain-containing protein.	0.688

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Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.527

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0048284

Organelle fusion

9 of 42

2.12

5.88

5.82e-15

GO:0007033

Vacuole organization

7 of 39

2.05

4.21

1.96e-10

GO:0016050

Vesicle organization

7 of 47

1.96

3.92

4.31e-10

GO:0034058

Endosomal vesicle fusion

4 of 4

2.79

3.84

7.14e-08

GO:0006906

Vesicle fusion

5 of 26

2.08

3.25

1.13e-07

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030897

HOPS complex

6 of 6

2.79

6.12

2.31e-12

GO:0099023

Vesicle tethering complex

7 of 42

2.01

4.33

5.16e-11

GO:0033263

CORVET complex

4 of 4

2.79

4.06

2.76e-08

GO:0005768

Endosome

9 of 114

1.69

3.63

3.04e-12

GO:0005770

Late endosome

4 of 30

1.92

2.31

1.14e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5225

HOPS complex, and Endosomal vesicle fusion

9 of 11

2.7

9.41

1.20e-19

CL:5223

RAB geranylgeranylation, and HOPS complex

10 of 31

2.3

8.06

1.20e-19

CL:5130

Mixed, incl. Vesicle tethering complex, and Membrane fusion

11 of 90

1.88

5.63

1.23e-18

CL:5227

HOPS complex

5 of 5

2.79

5.26

1.19e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04138

Autophagy - yeast

7 of 78

1.74

3.23

1.63e-09

map04145

Phagosome

3 of 52

1.55

1.04

0.0055

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5663205

Infectious disease

5 of 31

2.0

2.76

1.24e-06

MAP-1643685

Disease

5 of 40

1.89

2.56

2.00e-06

MAP-8873719

RAB geranylgeranylation

3 of 16

2.06

1.57

0.00089

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030897

HOPS complex

7 of 8

2.73

7.13

1.40e-14

GOCC:0042597

Periplasmic space

2 of 5

2.39

1.11

0.0089

GOCC:0016020

Membrane

8 of 964

0.71

0.53

0.0041

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000547

Clathrin, heavy chain/VPS, 7-fold repeat

4 of 5

2.69

3.22

9.97e-07

IPR045111

Vacuolar protein sorting-associated protein Vps41/Vps8

2 of 2

2.79

1.0

0.0153

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00175

Rab subfamily of small GTPases

2 of 10

2.09

0.9

0.0205

SM00184

Ring finger

3 of 50

1.57

0.84

0.0186

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