STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
NTH1-2Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (224 aa)    
Predicted Functional Partners:
A0A1Y1XE21
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
 
 0.988
A0A1Y1XUC8
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
 
 0.933
A0A1Y1XX56
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
    
 0.902
A0A1Y1Y786
AP endonuclease.
  
 
 0.878
A0A1Y1XRR9
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
  
 
 0.863
UNG1
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.863
A0A1Y1Z5L2
DNA glycosylase/AP lyase.
  
  
 0.840
A0A1Y1XTG5
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
    
 0.758
A0A1Y1Z1B5
MutL-like protein 1, colon cancer, nonpolyposis type 2.
   
 
 0.697
A0A1Y1Z9K3
Adenosylhomocysteinase.
  
 
  0.694
Your Current Organism:
Basidiobolus meristosporus
NCBI taxonomy Id: 1314790
Other names: B. meristosporus CBS 931.73, Basidiobolus meristosporus CBS 931.73
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