node1 | node2 | node1 annotation | node2 annotation | score |
A0A1Y1X5X8 | A0A1Y1XCR7 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Glutamate-5-semialdehyde dehydrogenase. | 0.549 |
A0A1Y1X5X8 | A0A1Y1XRU6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Glutamate synthase. | 0.794 |
A0A1Y1X5X8 | A0A1Y1YHX9 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Glutamate synthase. | 0.794 |
A0A1Y1X5X8 | A0A1Y1YLU4 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.506 |
A0A1Y1X5X8 | A0A1Y1YQT5 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Class I glutamine amidotransferase-like protein. | 0.822 |
A0A1Y1X5X8 | A0A1Y1Z4C6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | NADPH:adrenodoxin oxidoreductase, mitochondrial. | 0.799 |
A0A1Y1X5X8 | A0A1Y1Z8X0 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Glutamate 5-kinase. | 0.728 |
A0A1Y1XCR7 | A0A1Y1X5X8 | Glutamate-5-semialdehyde dehydrogenase. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.549 |
A0A1Y1XCR7 | A0A1Y1XRU6 | Glutamate-5-semialdehyde dehydrogenase. | Glutamate synthase. | 0.815 |
A0A1Y1XCR7 | A0A1Y1Y185 | Glutamate-5-semialdehyde dehydrogenase. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.858 |
A0A1Y1XCR7 | A0A1Y1Y9F9 | Glutamate-5-semialdehyde dehydrogenase. | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.814 |
A0A1Y1XCR7 | A0A1Y1YF85 | Glutamate-5-semialdehyde dehydrogenase. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.843 |
A0A1Y1XCR7 | A0A1Y1YHX9 | Glutamate-5-semialdehyde dehydrogenase. | Glutamate synthase. | 0.815 |
A0A1Y1XCR7 | A0A1Y1YLU4 | Glutamate-5-semialdehyde dehydrogenase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.791 |
A0A1Y1XCR7 | A0A1Y1YQT5 | Glutamate-5-semialdehyde dehydrogenase. | Class I glutamine amidotransferase-like protein. | 0.532 |
A0A1Y1XCR7 | A0A1Y1Z4C6 | Glutamate-5-semialdehyde dehydrogenase. | NADPH:adrenodoxin oxidoreductase, mitochondrial. | 0.832 |
A0A1Y1XCR7 | A0A1Y1Z8X0 | Glutamate-5-semialdehyde dehydrogenase. | Glutamate 5-kinase. | 0.998 |
A0A1Y1XRU6 | A0A1Y1X5X8 | Glutamate synthase. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.794 |
A0A1Y1XRU6 | A0A1Y1XCR7 | Glutamate synthase. | Glutamate-5-semialdehyde dehydrogenase. | 0.815 |
A0A1Y1XRU6 | A0A1Y1Y185 | Glutamate synthase. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.748 |