STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATO7_12243Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (151 aa)    
Predicted Functional Partners:
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
  
 0.976
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.914
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.881
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.874
ATO7_04785
Putative beta-lactamase; COG0491 Zn-dependent hydrolases, including glyoxylases.
     
 0.872
ATO7_01520
Flavin reductase-like, FMN-binding protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.
  
 
 0.820
argA
N-acetylglutamate synthase; COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.
    
  0.699
ATO7_12248
Multi-sensor hybrid histidine kinase; COG2202 FOG: PAS/PAC domain.
  
  
 0.631
ATO7_01335
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.625
ATO7_04025
Beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
   
 
 0.577
Your Current Organism:
Oceanococcus atlanticus
NCBI taxonomy Id: 1317117
Other names: CGMCC 1.12317, LMG 27155, LMG:27155, MCCC 1A09384, Maricoccus atlantica, O. atlanticus, Oceanococcus atlanticus Li et al. 2014, Thioalkalivibrio sp. 22II-S10r2, strain 22II-S10r2
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