STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa)    
Predicted Functional Partners:
trpF
COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
 
 
 0.999
ATO7_13198
Hypothetical protein; COG0147 Anthranilate/para-aminobenzoate synthases component I.
 0.999
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 0.999
ATO7_15522
Glutamine amidotransferase; COG0512 Anthranilate/para-aminobenzoate synthases component II.
 
 0.999
trpC
COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.991
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.983
ATO7_00360
COG1605 Chorismate mutase.
 
 
 0.973
ATO7_06860
COG0133 Tryptophan synthase beta chain.
 
 0.971
ATO7_00005
DNA-binding transcriptional activator SdiA; COG2771 DNA-binding HTH domain-containing proteins.
 
      0.899
Your Current Organism:
Oceanococcus atlanticus
NCBI taxonomy Id: 1317117
Other names: CGMCC 1.12317, LMG 27155, LMG:27155, MCCC 1A09384, Maricoccus atlantica, O. atlanticus, Oceanococcus atlanticus Li et al. 2014, Thioalkalivibrio sp. 22II-S10r2, strain 22II-S10r2
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