STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mecANegative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. (223 aa)    
Predicted Functional Partners:
GAM14843.1
ATP-dependent Clp protease, ATP-binding subunit ClpC/negative regulator of genetic competence clcC/mecB; Belongs to the ClpA/ClpB family.
    
 
 0.948
GAM13756.1
ClpB protein; Belongs to the ClpA/ClpB family.
    
 
 0.857
clpB
ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
    
 
 0.857
GAM13488.1
Acetyltransferase, GNAT family.
    
 
 0.766
GAM13489.1
Hypothetical protein.
    
 
 0.766
GAM16403.1
DNA replication intiation control protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.693
GAM16587.1
YjbH-like, GTP pyrophosphokinase domain.
  
  
 0.636
GAM12767.1
Uncharacterized SAV1743 homolog; Belongs to the UPF0354 family.
  
     0.622
GAM15956.1
Thioredoxin; Belongs to the thioredoxin family.
   
    0.594
GAM13271.1
Hypothetical protein SA_21.
  
     0.590
Your Current Organism:
Bacillus selenatarsenatis
NCBI taxonomy Id: 1321606
Other names: B. selenatarsenatis SF-1, Bacillus selenatarsenatis SF-1, Bacillus sp. SF-1
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