STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nagZbeta-L-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (348 aa)    
Predicted Functional Partners:
nagK
N-acetyl-D-glucosamine kinase; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
    
 0.979
anmK
anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
  
 0.811
ERH29012.1
Histidine triad domain protein; KEGG: hiz:R2866_1420 2.5e-52 hinT; Purine nucleoside phosphoramidase; Psort location: Cytoplasmic, score: 9.26.
     
 0.796
ERH29013.1
Hypothetical protein; KEGG: hip:CGSHiEE_07160 2.2e-14 ileS; isoleucyl-tRNA synthetase.
       0.796
rlmC
23S rRNA (uracil-5-)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
       0.796
ERH28833.1
KEGG: aap:NT05HA_0610 3.6e-156 N-acetylmuramoyl-L-alanine amidase; K01448 N-acetylmuramoyl-L-alanine amidase; Psort location: OuterMembrane, score: 9.49.
     
 0.541
mpl
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
  
   
 0.534
ERH28968.1
KEGG: aap:NT05HA_0337 1.9e-278 PTS system transporter subunit IIBC; K02778 PTS system, glucose-specific IIB component K02779; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.528
ERH27042.1
Hypothetical protein; KEGG: shn:Shewana3_2825 1.2e-13 dTDP-4-dehydrorhamnose 3,5-epimerase K01790.
     
  0.499
ERH27957.1
KEGG: pmu:PM1387 7.7e-209 nadR; nicotinamide-nucleotide adenylyltransferase K06211; Psort location: Cytoplasmic, score: 8.96.
      
 0.493
Your Current Organism:
Aggregatibacter sp. W10330
NCBI taxonomy Id: 1321772
Other names: A. sp. oral taxon 458 str. W10330, Aggregatibacter sp. oral taxon 458 str. W10330
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