STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiBTranscription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (98 aa)    
Predicted Functional Partners:
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.828
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.806
ERH33136.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.627
whiA
Putative BCR; Involved in cell division and chromosome segregation.
  
   
 0.627
ERH32535.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.589
ERH32084.1
KEGG: apb:SAR116_0174 0.0013 MerR family transcriptional regulator; Psort location: Cytoplasmic, score: 7.50.
 
     0.561
ERH21232.1
Hypothetical protein; KEGG: mpi:Mpet_2337 1.7e-12 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 7.50.
  
     0.560
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.532
ERH32087.1
DsbA-like protein; KEGG: rer:pREL1_0232 3.1e-31 putative disulfide bond formation protein; Psort location: Cellwall, score: 8.75.
       0.520
ERH32085.1
Hypothetical protein.
       0.510
Your Current Organism:
Actinomyces sp. F0311
NCBI taxonomy Id: 1321775
Other names: A. sp. oral taxon 172 str. F0311, Actinomyces sp. oral taxon 172 str. F0311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.