STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERH24836.1Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (330 aa)    
Predicted Functional Partners:
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.991
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.989
ERH28889.1
KEGG: pad:TIIST44_10395 4.2e-146 glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 0.989
pgi
KEGG: ahe:Arch_1289 1.3e-220 glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 
 0.987
pgk
Phosphoglycerate kinase; KEGG: mcu:HMPREF0573_11609 1.0e-151 pgk; phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.97.
  
 0.986
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 
 0.975
ERH32185.1
Transketolase; KEGG: cfl:Cfla_1934 5.8e-252 transketolase; K00615 transketolase; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family.
  
 
 0.974
ERH28866.1
Pyruvate kinase; KEGG: bcv:Bcav_2215 5.2e-171 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
  
 0.974
pfp
Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
 
 0.964
ERH32401.1
Putative PTS system sucrose-specific IIBC component; KEGG: rmu:RMDY18_04360 3.7e-177 phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific; K02808 PTS system, sucrose-specific IIA component; K02809 PTS system, sucrose-specific IIB component K02810; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.964
Your Current Organism:
Actinomyces sp. F0311
NCBI taxonomy Id: 1321775
Other names: A. sp. oral taxon 172 str. F0311, Actinomyces sp. oral taxon 172 str. F0311
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.