STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERI92515.1KEGG: spr:spr1101 9.3e-83 type II restriction endonuclease, putative K01155; Psort location: Cytoplasmic, score: 7.50. (1351 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.966
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.963
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.963
ERI92514.1
Hypothetical protein; KEGG: spd:SPD_1080 3.7e-51 type II restriction endonuclease; K01155 type II restriction enzyme; Psort location: Cytoplasmic, score: 7.50.
     0.948
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.948
ERI93912.1
Hypothetical protein; KEGG: nce:NCER_100357 0.0089 hypothetical protein; K10866 DNA repair protein RAD50; Psort location: Cytoplasmic, score: 7.50.
   
 0.920
ERI92638.1
DEAD2 domain protein; KEGG: cno:NT01CX_0936 2.1e-263 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50.
   
 0.920
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.815
ERI92513.1
Hypothetical protein; KEGG: ral:Rumal_2514 6.5e-10 XRE family transcriptional regulator K00558; Psort location: Cytoplasmic, score: 7.50.
       0.784
ERI90665.1
MT-A70 protein; KEGG: spj:MGAS2096_Spy1128 5.3e-52 adenine-specific methyltransferase K00571; Psort location: Cytoplasmic, score: 7.50; Belongs to the MT-A70-like family.
  
    0.772
Your Current Organism:
Clostridiales bacterium F0540
NCBI taxonomy Id: 1321778
Other names: C. bacterium oral taxon 876 str. F0540, Clostridiales bacterium oral taxon 876 str. F0540
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