STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BN4_11330RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)    
Predicted Functional Partners:
BN4_11331
Homologs of previously reported genes of unknown function.
       0.773
BN4_11332
Homologs of previously reported genes of unknown function.
       0.770
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.746
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.740
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.720
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.719
BN4_10572
Putative Anti-FecI sigma factor, FecR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.605
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.581
BN4_11968
PAS/PAC sensor hybrid histidine kinase (fragment).
  
 
 0.560
BN4_12411
Tetratricopeptide domain protein; Function of strongly homologous gene; regulator.
 
  
 0.549
Your Current Organism:
Pseudodesulfovibrio piezophilus
NCBI taxonomy Id: 1322246
Other names: Desulfovibrio piezophilus C1TLV30, Desulfovibrio piezophilus DSM 21447, Desulfovibrio piezophilus JCM 15486, Desulfovibrio sp. C1TLV30, P. piezophilus C1TLV30, Pseudodesulfovibrio piezophilus C1TLV30, Pseudodesulfovibrio piezophilus DSM 21447, Pseudodesulfovibrio piezophilus JCM 15486
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