STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R4FLT8_RHOPRPutative haloacid dehalogenase-like hydrolase. (248 aa)    
Predicted Functional Partners:
T1HRS2_RHOPR
A_deaminase domain-containing protein.
   
 0.919
T1HR77_RHOPR
Phosphoserine aminotransferase.
  
 
 0.914
T1ID10_RHOPR
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
    
 0.910
T1HB06_RHOPR
AFP-like domain-containing protein.
  
 
 0.905
T1HLC1_RHOPR
Nicotinamide-nucleotide adenylyltransferase.
    
 0.902
T1HZJ0_RHOPR
PNP_UDP_1 domain-containing protein.
  
 
 0.901
T1HMV7_RHOPR
Flavokinase domain-containing protein.
  
 
 0.899
R4G8P7_RHOPR
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.896
T1H9L5_RHOPR
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.882
T1HAT2_RHOPR
Uncharacterized protein.
    
 
 0.882
Your Current Organism:
Rhodnius prolixus
NCBI taxonomy Id: 13249
Other names: R. prolixus
Server load: low (16%) [HD]