STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R4G825_RHOPRPutative histone h1b. (188 aa)    
Predicted Functional Partners:
T1H8F0_RHOPR
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.954
T1I8R1_RHOPR
TPR_REGION domain-containing protein.
    
 0.936
T1H876_RHOPR
Histone H2A; Belongs to the histone H2A family.
   
 0.893
R4G4B9_RHOPR
Putative ribosomal protein l40.
    
 0.874
R4G538_RHOPR
Putative ubiquitin/ribosomal protein.
   
 0.869
T1I7H5_RHOPR
Uncharacterized protein.
   
 0.841
T1HWU7_RHOPR
Uncharacterized protein.
    
 0.838
R4FM54_RHOPR
Histone H3; Belongs to the histone H3 family.
   
 0.833
R4G370_RHOPR
Histone H3; Belongs to the histone H3 family.
   
 0.833
T1H8I3_RHOPR
Histone H3; Belongs to the histone H3 family.
   
 0.833
Your Current Organism:
Rhodnius prolixus
NCBI taxonomy Id: 13249
Other names: R. prolixus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.