node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | R4G4N7_RHOPR | T1HP16 | R4G4N7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.983 |
MCM7 | T1HES0_RHOPR | T1HP16 | T1HES0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Thymidylat_synt domain-containing protein. | 0.722 |
MCM7 | T1HUW2_RHOPR | T1HP16 | T1HUW2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.991 |
MCM7 | T1I0G8_RHOPR | T1HP16 | T1I0G8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.547 |
MCM7 | T1I159_RHOPR | T1HP16 | T1I159 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.908 |
MCM7 | T1IAU5_RHOPR | T1HP16 | T1IAU5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.966 |
R4FLX4_RHOPR | T1HQT3_RHOPR | R4FLX4 | T1HQT3 | Putative ribonuclease h1/h2 small subunit. | Uncharacterized protein. | 0.970 |
R4FLX4_RHOPR | T1I159_RHOPR | R4FLX4 | T1I159 | Putative ribonuclease h1/h2 small subunit. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.944 |
R4FM65_RHOPR | R4G4N7_RHOPR | R4FM65 | R4G4N7 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.904 |
R4FM65_RHOPR | R4G8J7_RHOPR | R4FM65 | R4G8J7 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.430 |
R4FM65_RHOPR | T1HES0_RHOPR | R4FM65 | T1HES0 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Thymidylat_synt domain-containing protein. | 0.938 |
R4FM65_RHOPR | T1HQT3_RHOPR | R4FM65 | T1HQT3 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Uncharacterized protein. | 0.563 |
R4FM65_RHOPR | T1HUW2_RHOPR | R4FM65 | T1HUW2 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.534 |
R4FM65_RHOPR | T1I0G8_RHOPR | R4FM65 | T1I0G8 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.601 |
R4FM65_RHOPR | T1I159_RHOPR | R4FM65 | T1I159 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.963 |
R4G4N7_RHOPR | MCM7 | R4G4N7 | T1HP16 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.983 |
R4G4N7_RHOPR | R4FM65_RHOPR | R4G4N7 | R4FM65 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.904 |
R4G4N7_RHOPR | R4G8J7_RHOPR | R4G4N7 | R4G8J7 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.598 |
R4G4N7_RHOPR | T1HES0_RHOPR | R4G4N7 | T1HES0 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Thymidylat_synt domain-containing protein. | 0.974 |
R4G4N7_RHOPR | T1HQT3_RHOPR | R4G4N7 | T1HQT3 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Uncharacterized protein. | 0.908 |