node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | T1HHG2_RHOPR | T1HP16 | T1HHG2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.999 |
MCM7 | T1HIB5_RHOPR | T1HP16 | T1HIB5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.998 |
MCM7 | T1HIE9_RHOPR | T1HP16 | T1HIE9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.991 |
MCM7 | T1HPM2_RHOPR | T1HP16 | T1HPM2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | T1I0X5_RHOPR | T1HP16 | T1I0X5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | T1I6R5_RHOPR | T1HP16 | T1I6R5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | T1I8X7_RHOPR | T1HP16 | T1I8X7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | CDT1 domain-containing protein. | 0.999 |
MCM7 | T1I9N9_RHOPR | T1HP16 | T1I9N9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | T1IA51_RHOPR | T1HP16 | T1IA51 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | T1IBZ5_RHOPR | T1HP16 | T1IBZ5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.999 |
T1HHG2_RHOPR | MCM7 | T1HHG2 | T1HP16 | Uncharacterized protein. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
T1HHG2_RHOPR | T1HIB5_RHOPR | T1HHG2 | T1HIB5 | Uncharacterized protein. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.990 |
T1HHG2_RHOPR | T1HIE9_RHOPR | T1HHG2 | T1HIE9 | Uncharacterized protein. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.916 |
T1HHG2_RHOPR | T1HPM2_RHOPR | T1HHG2 | T1HPM2 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
T1HHG2_RHOPR | T1I0X5_RHOPR | T1HHG2 | T1I0X5 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.998 |
T1HHG2_RHOPR | T1I6R5_RHOPR | T1HHG2 | T1I6R5 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
T1HHG2_RHOPR | T1I8X7_RHOPR | T1HHG2 | T1I8X7 | Uncharacterized protein. | CDT1 domain-containing protein. | 0.960 |
T1HHG2_RHOPR | T1I9N9_RHOPR | T1HHG2 | T1I9N9 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
T1HHG2_RHOPR | T1IA51_RHOPR | T1HHG2 | T1IA51 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
T1HHG2_RHOPR | T1IBZ5_RHOPR | T1HHG2 | T1IBZ5 | Uncharacterized protein. | Uncharacterized protein. | 0.969 |