STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESP89551.1Hypothetical protein; COG2150 Predicted regulator of amino acid metabolism, contains ACT domain. (166 aa)    
Predicted Functional Partners:
ESP88842.1
Proteasome rpn11 subunit jamm motif protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
  
     0.715
ESP89537.1
Cbs domain-containing protein; COG0517 FOG: CBS domain.
  
   
 0.708
ESP87780.1
Hypothetical protein; COG1395 Predicted transcriptional regulator.
  
     0.705
ESP88991.1
Phosphoserine phosphatase; COG1340 Uncharacterized archaeal coiled-coil protein.
  
     0.701
ESP88829.1
COG1860 Uncharacterized protein conserved in archaea; Belongs to the UPF0179 family.
  
     0.685
ESP88882.1
Prefoldin subunit alpha; COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit.
  
     0.666
ESP89550.1
Hypothetical protein.
       0.661
ESP89429.1
COG3388 Uncharacterized protein conserved in archaea.
  
     0.660
mptD
Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.649
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.630
Your Current Organism:
Halobonum tyrrellensis
NCBI taxonomy Id: 1324957
Other names: C. Halobonum tyrrellensis G22, Candidatus Halobonum tyrrellensis G22, Halobacteriaceae archaeon G22, Halobonum tyrrellensis G22
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.