STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rngRibonuclease G; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (502 aa)    
Predicted Functional Partners:
pnp
Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.917
yhbJ
Hypothetical protein; Displays ATPase and GTPase activities.
 
 
 
 0.879
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 
 0.871
rhlE
ATP-dependent RNA helicase RhlE.
    
 
 0.752
deaD
ATP-dependent RNA helicase DeaD; Belongs to the DEAD box helicase family.
    
 
 0.752
rhlE-2
ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family.
    
 
 0.752
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.661
smf
Putative Protein SMF, DNA protecting protein DprA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.649
rsmB
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.571
mrdA
Penicillin-binding protein 2.
  
    0.545
Your Current Organism:
Nitrospira japonica
NCBI taxonomy Id: 1325564
Other names: N. japonica, Nitrospira sp. NJ1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.