node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSJP_0545 | NSJP_3229 | NSJP_0545 | NSJP_3229 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Biotin/lipoate A/B protein ligase. | 0.867 |
NSJP_0545 | gcvH | NSJP_0545 | NSJP_3563 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.761 |
NSJP_0545 | gcvP | NSJP_0545 | NSJP_1359 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.678 |
NSJP_0545 | lipA | NSJP_0545 | NSJP_3401 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.662 |
NSJP_0545 | lipB | NSJP_0545 | NSJP_1495 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.680 |
NSJP_0545 | lpd-2 | NSJP_0545 | NSJP_3562 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Dihydrolipoyl dehydrogenase. | 0.994 |
NSJP_3229 | NSJP_0545 | NSJP_3229 | NSJP_0545 | Biotin/lipoate A/B protein ligase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.867 |
NSJP_3229 | NSJP_3231 | NSJP_3229 | NSJP_3231 | Biotin/lipoate A/B protein ligase. | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.945 |
NSJP_3229 | gcvH | NSJP_3229 | NSJP_3563 | Biotin/lipoate A/B protein ligase. | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.982 |
NSJP_3229 | lipA | NSJP_3229 | NSJP_3401 | Biotin/lipoate A/B protein ligase. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.934 |
NSJP_3229 | lipB | NSJP_3229 | NSJP_1495 | Biotin/lipoate A/B protein ligase. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.928 |
NSJP_3229 | lpd-2 | NSJP_3229 | NSJP_3562 | Biotin/lipoate A/B protein ligase. | Dihydrolipoyl dehydrogenase. | 0.878 |
NSJP_3231 | NSJP_3229 | NSJP_3231 | NSJP_3229 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Biotin/lipoate A/B protein ligase. | 0.945 |
NSJP_3231 | gcvH | NSJP_3231 | NSJP_3563 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.761 |
NSJP_3231 | gcvP | NSJP_3231 | NSJP_1359 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.678 |
NSJP_3231 | lipA | NSJP_3231 | NSJP_3401 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.580 |
NSJP_3231 | lipB | NSJP_3231 | NSJP_1495 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.592 |
NSJP_3231 | lpd-2 | NSJP_3231 | NSJP_3562 | Branched-chain alpha-keto acid dehydrogenase subunit E2. | Dihydrolipoyl dehydrogenase. | 0.998 |
NSJP_3402 | NSJP_3403 | NSJP_3402 | NSJP_3403 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.685 |
NSJP_3402 | lipA | NSJP_3402 | NSJP_3401 | Homologs of previously reported genes of unknown function. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.636 |