STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP52_016364NACHT domain-containing protein. (836 aa)    
Predicted Functional Partners:
CEP52_014893
PAB-dependent poly(A)-specific ribonuclease subunit PAN3.
    
 0.799
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]
    
 0.799
CEP52_001988
Vezatin domain-containing protein.
  
 0.771
CEP52_001989
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.771
CEP52_001582
Exonuclease domain-containing protein.
   
 0.709
CEP52_010918
60S ribosomal protein L7.
   
 0.634
CEP52_007118
GMP synthase [glutamine-hydrolyzing].
     
 0.583
CEP52_017680
UvrD_C_2 domain-containing protein.
  
 
 0.556
CEP52_011108
Uncharacterized protein.
  
 
 0.556
CEP52_006880
UvrD_C_2 domain-containing protein.
  
 
 0.556
Your Current Organism:
Fusarium sp. AF4
NCBI taxonomy Id: 1325735
Other names: F. sp. AF-4, Fusarium sp. AF-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.