STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN1Protein tyrosine phosphatase non-receptor type 1. (435 aa)    
Predicted Functional Partners:
INSR
Insulin receptor.
    
 0.978
IRS1
Insulin receptor substrate 1.
    
 0.974
CTNNB1
Catenin beta 1.
    
 0.943
IRS4
Insulin receptor substrate 4.
    
 0.942
IRS2
Insulin receptor substrate 2.
    
 0.939
CDH2
Cadherin 2.
    
 
 0.933
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
    
 0.905
IGF1R
Insulin like growth factor 1 receptor.
    
 0.873
INSRR
Insulin receptor related receptor.
    
 0.873
STAT3
Signal transducer and activator of transcription 3.
   
 0.860
Your Current Organism:
Anser brachyrhynchus
NCBI taxonomy Id: 132585
Other names: A. brachyrhynchus, Pink-footed goose
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.