| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OLF49871.1 | OLF50413.1 | BU200_05095 | BU200_02060 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
| OLF49871.1 | dnaJ | BU200_05095 | BU200_05085 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.988 |
| OLF49871.1 | dnaK_1 | BU200_05095 | BU200_05090 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| OLF49871.1 | fusA | BU200_05095 | BU200_01900 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.405 |
| OLF49871.1 | groEL | BU200_05095 | BU200_02065 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.984 |
| OLF49871.1 | guaB | BU200_05095 | BU200_06560 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.469 |
| OLF49871.1 | sigA | BU200_05095 | BU200_04650 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.432 |
| OLF49871.1 | trxA_1 | BU200_05095 | BU200_00935 | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | GNAT family N-acetyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. | 0.464 |
| OLF50311.1 | dnaK_1 | BU200_02795 | BU200_05090 | Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.500 |
| OLF50311.1 | fusA | BU200_02795 | BU200_01900 | Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.409 |
| OLF50311.1 | groEL | BU200_02795 | BU200_02065 | Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.835 |
| OLF50413.1 | OLF49871.1 | BU200_02060 | BU200_05095 | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
| OLF50413.1 | dnaJ | BU200_02060 | BU200_05085 | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.752 |
| OLF50413.1 | dnaK_1 | BU200_02060 | BU200_05090 | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.964 |
| OLF50413.1 | groEL | BU200_02060 | BU200_02065 | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.999 |
| OLF50413.1 | guaB | BU200_02060 | BU200_06560 | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.530 |
| OLF50413.1 | sigA | BU200_02060 | BU200_04650 | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.445 |
| OLF50413.1 | trxA_1 | BU200_02060 | BU200_00935 | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | GNAT family N-acetyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. | 0.423 |
| dnaJ | OLF49871.1 | BU200_05085 | BU200_05095 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Nucleotide exchange factor GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.988 |
| dnaJ | OLF50413.1 | BU200_05085 | BU200_02060 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Co-chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.752 |
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