OLF50360.1 protein (Streptococcus acidominimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Streptococcus acidominimus

NCBI taxonomy Id: 1326
Other names: ATCC 51725, CCUG 27296, CIP 82.4, DSM 20622, LMG 17755, LMG:17755, NCDO 2025, NCIMB 702025, NCTC 12957, S. acidominimus

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OLF49513.1	OLF50360.1	BU200_06960	BU200_02440	Glyoxalase/bleomycin resistance/extradiol dioxygenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.410
OLF49534.1	OLF50360.1	BU200_06775	BU200_02440	Deacetylase SIR2; Derived by automated computational analysis using gene prediction method: Protein Homology.	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.462
OLF49534.1	OLF50404.1	BU200_06775	BU200_02010	Deacetylase SIR2; Derived by automated computational analysis using gene prediction method: Protein Homology.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.533
OLF50129.1	OLF50360.1	BU200_03485	BU200_02440	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.656
OLF50332.1	OLF50360.1	BU200_02275	BU200_02440	GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.454
OLF50358.1	OLF50360.1	BU200_02430	BU200_02440	Derived by automated computational analysis using gene prediction method: Protein Homology.	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.442
OLF50358.1	thiI	BU200_02430	BU200_02435	Derived by automated computational analysis using gene prediction method: Protein Homology.	tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.957
OLF50360.1	OLF49513.1	BU200_02440	BU200_06960	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glyoxalase/bleomycin resistance/extradiol dioxygenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.410
OLF50360.1	OLF49534.1	BU200_02440	BU200_06775	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Deacetylase SIR2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.462
OLF50360.1	OLF50129.1	BU200_02440	BU200_03485	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.656
OLF50360.1	OLF50332.1	BU200_02440	BU200_02275	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.454
OLF50360.1	OLF50358.1	BU200_02440	BU200_02430	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Derived by automated computational analysis using gene prediction method: Protein Homology.	0.442
OLF50360.1	OLF50361.1	BU200_02440	BU200_02445	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.429
OLF50360.1	OLF50362.1	BU200_02440	BU200_02450	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.422
OLF50360.1	OLF50404.1	BU200_02440	BU200_02010	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.453
OLF50360.1	thiI	BU200_02440	BU200_02435	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.448
OLF50361.1	OLF50360.1	BU200_02445	BU200_02440	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.429
OLF50361.1	OLF50362.1	BU200_02445	BU200_02450	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.757
OLF50362.1	OLF50360.1	BU200_02450	BU200_02440	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.422
OLF50362.1	OLF50361.1	BU200_02450	BU200_02445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.757