Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (442 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
0.963
OLF50133.1
Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.898
OLF50132.1
Chromosome segregation protein SMC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.879
OLF50170.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.845
OLF49084.1
Preprotein translocase subunit SecG; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.844
OLF49964.1
Preprotein translocase subunit SecE; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.842
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
 
 
 0.831
OLF50131.1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.818
rpmC
50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family.
    
 
 0.808
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
 
 0.802
Your Current Organism:
Streptococcus acidominimus
NCBI taxonomy Id: 1326
Other names: ATCC 51725, CCUG 27296, CIP 82.4, DSM 20622, LMG 17755, LMG:17755, NCDO 2025, NCIMB 702025, NCTC 12957, S. acidominimus
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