STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A165FL46Ubiquitin-conjugating enzyme type E2; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)    
Predicted Functional Partners:
A0A165HBS2
Putative poly(A) RNA transport protein; Belongs to the ubiquitin-activating E1 family.
    
 0.888
A0A165JBR0
NEDD8 activating enzyme.
    
 0.845
A0A165JBP4
Putative ubiquitin-conjugating enzyme E2 W.
   
 0.830
A0A165JRR9
UBC-like protein.
   
 0.818
A0A165H2N8
Ubiquitin-conjugating enzyme E2 6.
     
 0.810
A0A164ZNI6
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.
    
 0.804
A0A165A8Y2
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.790
A0A164ZJN1
ThiF domain-containing protein.
    
 0.786
A0A164ZRE0
Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family.
    
 0.786
uba4
Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
    
 0.786
Your Current Organism:
Xylona heveae
NCBI taxonomy Id: 1328760
Other names: X. heveae TC161, Xylona heveae TC161
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