A0A165HAI1 protein (Xylona heveae) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

A0A165HAI1

Kinetochore protein nuf2. (470 aa)

Predicted Functional Partners:

A0A165GR93

0.999

A0A165IXS7

0.999

A0A164ZEX8

0.975

A0A165GPG7

0.975

A0A165HF76

0.946

A0A164ZX35

0.945

A0A165IGS7

0.933

A0A165I144

0.932

A0A161TQ64

0.930

A0A165K143

0.922

Your Current Organism:

Xylona heveae

NCBI taxonomy Id: 1328760
Other names: X. heveae TC161, Xylona heveae TC161

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A161TQ64	A0A164ZEX8	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	HORMA domain-containing protein.	0.928
A0A161TQ64	A0A165GPG7	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.929
A0A161TQ64	A0A165GR93	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	HEC/Ndc80p family protein.	0.837
A0A161TQ64	A0A165HAI1	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinetochore protein nuf2.	0.930
A0A161TQ64	A0A165I144	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein-like protein bimC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.975
A0A161TQ64	A0A165IGS7	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	ARM repeat-containing protein.	0.750
A0A161TQ64	A0A165K143	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.957
A0A164ZEX8	A0A161TQ64	HORMA domain-containing protein.	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.928
A0A164ZEX8	A0A164ZX35	HORMA domain-containing protein.	Uncharacterized protein.	0.720
A0A164ZEX8	A0A165GPG7	HORMA domain-containing protein.	Uncharacterized protein.	0.999
A0A164ZEX8	A0A165GR93	HORMA domain-containing protein.	HEC/Ndc80p family protein.	0.973
A0A164ZEX8	A0A165HAI1	HORMA domain-containing protein.	Kinetochore protein nuf2.	0.975
A0A164ZEX8	A0A165I144	HORMA domain-containing protein.	Kinesin-like protein-like protein bimC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.949
A0A164ZEX8	A0A165IGS7	HORMA domain-containing protein.	ARM repeat-containing protein.	0.891
A0A164ZEX8	A0A165IXS7	HORMA domain-containing protein.	Uncharacterized protein.	0.922
A0A164ZEX8	A0A165K143	HORMA domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.890
A0A164ZX35	A0A164ZEX8	Uncharacterized protein.	HORMA domain-containing protein.	0.720
A0A164ZX35	A0A165GPG7	Uncharacterized protein.	Uncharacterized protein.	0.714
A0A164ZX35	A0A165GR93	Uncharacterized protein.	HEC/Ndc80p family protein.	0.897
A0A164ZX35	A0A165HAI1	Uncharacterized protein.	Kinetochore protein nuf2.	0.945

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.636

expected number of edges:

15

PPI enrichment p-value:

2.32e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005978

Glycogen biosynthetic process

3 of 8

2.35

1.83

0.00036

GO:0005975

Carbohydrate metabolic process

7 of 326

1.1

1.03

0.00029

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016758

Hexosyltransferase activity

3 of 17

2.02

1.33

0.0027

GO:0102752

1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)

2 of 5

2.37

0.94

0.0186

GO:0003844

1,4-alpha-glucan branching enzyme activity

2 of 5

2.37

0.94

0.0186

GO:0004553

Hydrolase activity, hydrolyzing O-glycosyl compounds

3 of 50

1.55

0.83

0.0186

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 344

0.94

0.57

0.0211

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4821

Starch and sucrose metabolism, and Amino acid/polyamine transporter I

10 of 26

2.36

8.34

9.26e-20

CL:4825

Glycogen metabolic process, and Alpha-amylase domain

6 of 13

2.44

5.31

1.86e-11

CL:4863

Amino acid/polyamine transporter I, and Alpha amylase, catalytic domain

4 of 5

2.68

3.8

7.03e-08

CL:4827

Glycosyl hydrolase, all-beta

4 of 7

2.53

3.55

1.67e-07

CL:4841

Glycogen biosynthesis, and Carbohydrate phosphorylase

2 of 5

2.37

1.21

0.0058

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pls00500

Starch and sucrose metabolism

7 of 27

2.19

5.23

1.99e-12

pls01110

Biosynthesis of secondary metabolites

6 of 327

1.04

0.94

0.00036

pls01100

Metabolic pathways

7 of 701

0.77

0.62

0.0014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031588

Nucleotide-activated protein kinase complex

2 of 6

2.3

0.94

0.0189

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0320

Glycogen biosynthesis

3 of 5

2.55

2.35

4.14e-05

KW-0119

Carbohydrate metabolism

3 of 14

2.1

1.84

0.00025

KW-0321

Glycogen metabolism

2 of 3

2.6

1.57

0.0013

KW-0328

Glycosyltransferase

4 of 69

1.54

1.47

0.00031

KW-0326

Glycosidase

3 of 36

1.69

1.35

0.0013

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00324

Amino acid permease

3 of 3

2.77

2.35

4.81e-05

PF00128

Alpha amylase, catalytic domain

3 of 10

2.25

1.82

0.00034

PF16657

Maltogenic Amylase, C-terminal domain

2 of 2

2.77

1.35

0.0035

PF02806

Alpha amylase, C-terminal all-beta domain

2 of 2

2.77

1.35

0.0035

PF02922

Carbohydrate-binding module 48 (Isoamylase N-terminal domain)

2 of 6

2.3

1.09

0.0097

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR013780

Glycosyl hydrolase, all-beta

5 of 8

2.57

4.17

1.02e-08

IPR006047

Glycosyl hydrolase, family 13, catalytic domain

5 of 12

2.39

3.86

2.44e-08

IPR017853

Glycoside hydrolase superfamily

5 of 27

2.04

2.95

5.23e-07

IPR045857

Oligo-1,6-glucosidase, domain 2

2 of 2

2.77

1.2

0.0066

IPR044143

Glycogen branching enzyme GlgB, N-terminal Early set domain

2 of 2

2.77

1.2

0.0066

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00642

Alpha-amylase domain

2 of 2

2.77

1.5

0.0019

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