STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZWILCHZwilch kinetochore protein. (589 aa)    
Predicted Functional Partners:
KNTC1
Kinetochore associated 1.
   
 0.999
ZW10
Zw10 kinetochore protein.
    
 0.999
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.917
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.892
ENSPVAP00000016105
annotation not available
   
 0.867
SKA1
Spindle and kinetochore associated complex subunit 1.
   
  
 0.847
MELK
Maternal embryonic leucine zipper kinase.
   
  
 0.839
BUB3
BUB3 mitotic checkpoint protein.
     
 0.818
KIF11
Kinesin family member 11.
   
  
 0.811
ENSPVAP00000007118
annotation not available
   
  
 0.803
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.