STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YES1YES proto-oncogene 1, Src family tyrosine kinase. (540 aa)    
Predicted Functional Partners:
PTK2
Protein tyrosine kinase 2.
   
0.912
CTNND1
Catenin delta 1.
    
 0.909
EGFR
Epidermal growth factor receptor.
    
0.907
FER
FER tyrosine kinase.
   
 
0.901
SRMS
Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites.
  
0.887
ESR1
Estrogen receptor 1.
    
 0.886
PTK6
Protein tyrosine kinase 6.
  
0.886
FYN
FYN proto-oncogene, Src family tyrosine kinase.
  
0.884
STAT3
Signal transducer and activator of transcription 3.
   
 0.876
PTK2B
Protein tyrosine kinase 2 beta.
   
0.873
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.