STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH1Notch receptor 1. (2472 aa)    
Predicted Functional Partners:
JAG1
Jagged canonical Notch ligand 1.
    
0.997
DLL4
Delta like canonical Notch ligand 4.
    
0.996
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.995
JAG2
Jagged canonical Notch ligand 2.
    
0.993
ENSPVAP00000010952
annotation not available
    
0.992
MAML1
Mastermind like transcriptional coactivator 1.
    
 0.992
PSEN1
Presenilin 1.
    
 0.986
ENSPVAP00000008194
annotation not available
     
0.984
NCSTN
Nicastrin.
    
 0.981
DTX1
Deltex E3 ubiquitin ligase 1.
    
 0.970
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.