STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSDMEGasdermin E. (497 aa)    
Predicted Functional Partners:
CYCS
Cytochrome c, somatic.
     
 0.896
GSDMB
Gasdermin B.
      
 0.797
GSDMD
Gasdermin D.
      
 0.761
MLKL
Mixed lineage kinase domain like pseudokinase.
      
 0.738
CASP3
Caspase 3.
     
 0.726
ENSPVAP00000012858
annotation not available
     
 0.722
ENSPVAP00000012861
annotation not available
     
 0.722
ENSPVAP00000001703
annotation not available
      
 0.700
IL18
Interleukin 18.
      
 0.694
GZMA
Granzyme A.
     
 0.679
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.