STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B1SH2B adaptor protein 1. (754 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.961
JAK2
Janus kinase 2.
    
 0.945
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.942
NTRK3
Neurotrophic receptor tyrosine kinase 3.
    
 0.912
ENSPVAP00000007095
annotation not available
    
 0.906
SH2B3
SH2B adaptor protein 3.
    
0.893
INSR
Insulin receptor.
    
 0.890
CBL
Cbl proto-oncogene.
    
 0.837
JAK3
Janus kinase 3.
    
 0.807
CBLB
Cbl proto-oncogene B.
    
 0.802
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.