STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PICALMPhosphatidylinositol binding clathrin assembly protein. (657 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.985
ITSN2
Intersectin 2.
    
 0.984
ITSN1
Intersectin 1.
    
 0.957
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.920
CLTCL1
Clathrin heavy chain like 1.
    
 0.912
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 0.902
CLTC
Clathrin heavy chain.
    
 0.890
AP2A1
Adaptor related protein complex 2 subunit alpha 1.
   
 0.882
AP2M1
Adaptor related protein complex 2 subunit mu 1.
    
 0.868
CLINT1
Clathrin interactor 1.
    
 0.846
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.