STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM10ADAM metallopeptidase domain 10. (748 aa)    
Predicted Functional Partners:
CDH1
Cadherin 1.
     
 0.966
ADAM17
ADAM metallopeptidase domain 17.
     
0.928
TSPAN5
Tetraspanin 5.
   
 0.863
APP
Amyloid beta precursor protein.
    
 0.852
TSPAN15
Tetraspanin 15.
    
 0.830
BACE1
Beta-secretase 1.
    
 
 0.811
ENSPVAP00000010952
annotation not available
    
 0.807
TSPAN33
Tetraspanin 33.
    
 0.798
EFNA2
Ephrin A2.
    
 0.797
TSPAN14
Tetraspanin 14.
   
 0.794
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.