STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1245 aa)    
Predicted Functional Partners:
BRCA1
BRCA1 DNA repair associated.
   
 0.984
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.980
MLH1
mutL homolog 1.
   
 0.976
WRN
WRN RecQ like helicase.
  
 0.953
PMS2
PMS1 homolog 2, mismatch repair system component.
   
 0.952
BARD1
BRCA1 associated RING domain 1.
  
 0.947
PALB2
Partner and localizer of BRCA2.
   
 0.938
BRCA2
BRCA2 DNA repair associated.
   
 0.928
SLF1
SMC5-SMC6 complex localization factor 1.
  
 0.928
NBN
Nibrin.
    
 0.928
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.