STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KITKIT proto-oncogene, receptor tyrosine kinase. (976 aa)    
Predicted Functional Partners:
KITLG
KIT ligand.
   
 0.999
CSF1
Colony stimulating factor 1.
   
 0.981
GRB2
Growth factor receptor bound protein 2.
   
 0.979
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.978
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
   
 0.968
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.951
PTPRU
Protein tyrosine phosphatase receptor type U.
    
  0.951
ENSPVAP00000001922
annotation not available
    
 0.948
ENSPVAP00000012903
annotation not available
    
 0.948
KRAS
KRAS proto-oncogene, GTPase.
    
 0.946
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.