STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LEPRLeptin receptor. (1164 aa)    
Predicted Functional Partners:
LEP
Leptin.
    
 0.997
JAK2
Janus kinase 2.
    
 0.992
JAK3
Janus kinase 3.
    
 0.963
TYK2
Tyrosine kinase 2.
    
 0.952
JAK1
Janus kinase 1.
    
 0.952
IL7
Interleukin 7.
     
 0.942
POMC
Proopiomelanocortin.
      
 0.940
IL6
Interleukin 6.
     
 0.932
PRL
Prolactin.
     
 0.923
NPY
Neuropeptide Y.
      
 0.922
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.