STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAP2CRAP2C, member of RAS oncogene family. (92 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.906
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.881
ITSN1
Intersectin 1.
    
 0.870
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.839
RHOA
Ras homolog family member A.
   
  0.825
RAP1GAP
RAP1 GTPase activating protein.
    
 0.787
MST1R
Macrophage stimulating 1 receptor.
   
 0.787
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.787
NF1
Neurofibromin 1.
    
 0.771
ENSPVAP00000004293
annotation not available
   
 0.767
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
Server load: low (30%) [HD]