MAP3K1 protein (Pteropus vampyrus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pteropus vampyrus

NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN1	MAP2K1	ENSPVAP00000000516	ENSPVAP00000000060	Axin 1.	Mitogen-activated protein kinase kinase 1.	0.491
AXIN1	MAP3K1	ENSPVAP00000000516	ENSPVAP00000009165	Axin 1.	Mitogen-activated protein kinase kinase kinase 1.	0.985
CHUK	IKBKB	ENSPVAP00000007578	ENSPVAP00000013962	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.999
CHUK	IKBKG	ENSPVAP00000007578	ENSPVAP00000007068	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
CHUK	MAP3K1	ENSPVAP00000007578	ENSPVAP00000009165	Component of inhibitor of nuclear factor kappa B kinase complex.	Mitogen-activated protein kinase kinase kinase 1.	0.995
CHUK	TRAF2	ENSPVAP00000007578	ENSPVAP00000008630	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor associated factor 2.	0.996
CHUK	TRAF6	ENSPVAP00000007578	ENSPVAP00000004475	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor associated factor 6.	0.998
IKBKB	CHUK	ENSPVAP00000013962	ENSPVAP00000007578	Inhibitor of nuclear factor kappa B kinase subunit beta.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.999
IKBKB	IKBKG	ENSPVAP00000013962	ENSPVAP00000007068	Inhibitor of nuclear factor kappa B kinase subunit beta.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
IKBKB	MAP3K1	ENSPVAP00000013962	ENSPVAP00000009165	Inhibitor of nuclear factor kappa B kinase subunit beta.	Mitogen-activated protein kinase kinase kinase 1.	0.995
IKBKB	TRAF2	ENSPVAP00000013962	ENSPVAP00000008630	Inhibitor of nuclear factor kappa B kinase subunit beta.	TNF receptor associated factor 2.	0.995
IKBKB	TRAF6	ENSPVAP00000013962	ENSPVAP00000004475	Inhibitor of nuclear factor kappa B kinase subunit beta.	TNF receptor associated factor 6.	0.998
IKBKG	CHUK	ENSPVAP00000007068	ENSPVAP00000007578	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.999
IKBKG	IKBKB	ENSPVAP00000007068	ENSPVAP00000013962	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.999
IKBKG	MAP2K4	ENSPVAP00000007068	ENSPVAP00000013285	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Mitogen-activated protein kinase kinase 4.	0.509
IKBKG	MAP2K7	ENSPVAP00000007068	ENSPVAP00000002171	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Mitogen-activated protein kinase kinase 7.	0.426
IKBKG	MAP3K1	ENSPVAP00000007068	ENSPVAP00000009165	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Mitogen-activated protein kinase kinase kinase 1.	0.991
IKBKG	TRAF2	ENSPVAP00000007068	ENSPVAP00000008630	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor associated factor 2.	0.996
IKBKG	TRAF6	ENSPVAP00000007068	ENSPVAP00000004475	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor associated factor 6.	0.998
MAP2K1	AXIN1	ENSPVAP00000000060	ENSPVAP00000000516	Mitogen-activated protein kinase kinase 1.	Axin 1.	0.491