STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1Signal-induced proliferation-associated 1. (1040 aa)    
Predicted Functional Partners:
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.907
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.907
AFDN
Afadin, adherens junction formation factor.
    
 0.907
DPF2
Double PHD fingers 2.
      
 0.769
MAP3K11
Mitogen-activated protein kinase kinase kinase 11.
   
 
 0.720
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.708
RALB
RAS like proto-oncogene B.
    
 0.707
MRAS
Muscle RAS oncogene homolog.
    
 0.688
EPS8L1
EPS8 like 1.
      
 0.678
RAP2A
RAP2A, member of RAS oncogene family.
    
 0.633
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.