STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUFUSUFU negative regulator of hedgehog signaling. (484 aa)    
Predicted Functional Partners:
GLI1
GLI family zinc finger 1.
    
 0.999
GLI3
GLI family zinc finger 3.
    
 0.995
GLI2
GLI family zinc finger 2.
    
 0.991
STK36
Serine/threonine kinase 36.
    
 0.990
KIF7
Kinesin family member 7.
    
 0.982
GSK3B
Glycogen synthase kinase 3 beta.
    
 0.973
SMO
Smoothened, frizzled class receptor.
     
 0.972
SPOP
Speckle type BTB/POZ protein.
     
 0.969
ENSPVAP00000012211
annotation not available
     
 0.964
ULK4
Unc-51 like kinase 4.
    
 0.954
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.