STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B3SH2B adaptor protein 3. (377 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.918
NTRK3
Neurotrophic receptor tyrosine kinase 3.
    
 0.902
ENSPVAP00000007095
annotation not available
    
  0.901
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
  0.901
SH2B1
SH2B adaptor protein 1.
    
0.893
KITLG
KIT ligand.
     
 0.878
JAK2
Janus kinase 2.
    
 0.836
SETBP1
SET binding protein 1.
      
 0.769
IGF1R
Insulin like growth factor 1 receptor.
    
 0.762
INSR
Insulin receptor.
    
 0.762
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.