STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN21Protein tyrosine phosphatase non-receptor type 21. (1170 aa)    
Predicted Functional Partners:
FBXO42
F-box protein 42.
      
 0.730
SNAP47
Synaptosome associated protein 47.
     
 0.691
MTSS1
MTSS I-BAR domain containing 1.
    
 0.683
GRB2
Growth factor receptor bound protein 2.
    
 0.667
MST1R
Macrophage stimulating 1 receptor.
    
 0.647
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.647
YAP1
Yes associated protein 1.
   
 
 0.624
WWTR1
WW domain containing transcription regulator 1.
   
 
 0.624
FBXO6
F-box protein 6.
      
 0.621
PARD6B
Par-6 family cell polarity regulator beta.
    
 
 0.621
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.