STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKDCProtein kinase, DNA-activated, catalytic subunit. (4013 aa)    
Predicted Functional Partners:
XRCC6
X-ray repair cross complementing 6.
    
 0.993
XRCC5
X-ray repair cross complementing 5.
   
 0.993
TP53
Tumor protein p53.
    
 0.981
DCLRE1C
DNA cross-link repair 1C.
    
 0.979
LIG4
DNA ligase 4.
    
 0.973
RNF144A
Ring finger protein 144A.
    
 0.972
RPTOR
Regulatory associated protein of MTOR complex 1.
   
 0.920
RICTOR
RPTOR independent companion of MTOR complex 2.
   
 0.916
MLST8
MTOR associated protein, LST8 homolog.
    
 0.913
MAPKAP1
MAPK associated protein 1.
    
 0.913
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.