STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUMA1Nuclear mitotic apparatus protein 1. (2112 aa)    
Predicted Functional Partners:
GPSM2
G protein signaling modulator 2.
    
 
 0.938
CDK1
Cyclin dependent kinase 1.
   
 0.924
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2.
   
   0.763
GIGYF1
GRB10 interacting GYF protein 1.
   
    0.756
CCNB2
Cyclin B2.
   
  0.730
CCNB1
Cyclin B1.
   
  0.730
GPSM1
G protein signaling modulator 1.
    
 
 0.708
ENSPVAP00000011086
annotation not available
   
  0.701
KPNA2
Karyopherin subunit alpha 2.
   
 
 0.700
KPNA7
Karyopherin subunit alpha 7.
   
 
 0.700
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.