STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCG2Phospholipase C gamma 2. (1197 aa)    
Predicted Functional Partners:
SYK
Spleen associated tyrosine kinase.
   
0.991
BTK
Bruton tyrosine kinase.
   
 0.984
LCP2
Lymphocyte cytosolic protein 2.
   
 0.980
PDGFRB
Platelet derived growth factor receptor beta.
    
 0.974
LAT
Linker for activation of T cells.
    
 0.961
EGFR
Epidermal growth factor receptor.
    
 0.961
VAV1
Vav guanine nucleotide exchange factor 1.
   
0.955
BLNK
B cell linker.
   
 0.954
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.951
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.948
Your Current Organism:
Pteropus vampyrus
NCBI taxonomy Id: 132908
Other names: P. vampyrus, large flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.