A4X06_g6172 protein (Tilletia controversa) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

A4X06_g6172

Uncharacterized protein. (1503 aa)

Predicted Functional Partners:

A4X06_g4656

0.953

A4X06_g7736

0.769

A4X06_g2336

0.769

A4X06_g5390

0.683

A4X06_g1660

0.654

A4X06_g7360

0.649

A4X06_g2512

0.625

A4X06_g2218

0.625

A4X06_g2219

0.625

A4X06_g2217

0.625

Your Current Organism:

Tilletia controversa

NCBI taxonomy Id: 13291
Other names: T. controversa, Tilletia contraversa, dwarf bunt fungus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4X06_g1660	A4X06_g2217	A0A177VUC0	A0A177VSZ0	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.849
A4X06_g1660	A4X06_g2218	A0A177VUC0	A0A177VSK2	RING-type domain-containing protein.	Uncharacterized protein.	0.849
A4X06_g1660	A4X06_g2219	A0A177VUC0	A0A177VSN8	RING-type domain-containing protein.	Uncharacterized protein.	0.849
A4X06_g1660	A4X06_g2336	A0A177VUC0	A0A177VSB7	RING-type domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.995
A4X06_g1660	A4X06_g2512	A0A177VUC0	A0A177VQP6	RING-type domain-containing protein.	Uncharacterized protein.	0.905
A4X06_g1660	A4X06_g4656	A0A177VUC0	A0A177VJG4	RING-type domain-containing protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.999
A4X06_g1660	A4X06_g5390	A0A177VUC0	A0A177VHE7	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.988
A4X06_g1660	A4X06_g6172	A0A177VUC0	A0A177UZE3	RING-type domain-containing protein.	Uncharacterized protein.	0.654
A4X06_g1660	A4X06_g7360	A0A177VUC0	A0A177U6T2	RING-type domain-containing protein.	Uncharacterized protein.	0.814
A4X06_g1660	A4X06_g7736	A0A177VUC0	A0A177U3W0	RING-type domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.966
A4X06_g2217	A4X06_g1660	A0A177VSZ0	A0A177VUC0	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.849
A4X06_g2217	A4X06_g2336	A0A177VSZ0	A0A177VSB7	Ubiquitin-like domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.778
A4X06_g2217	A4X06_g2512	A0A177VSZ0	A0A177VQP6	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.839
A4X06_g2217	A4X06_g4656	A0A177VSZ0	A0A177VJG4	Ubiquitin-like domain-containing protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.898
A4X06_g2217	A4X06_g5390	A0A177VSZ0	A0A177VHE7	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.787
A4X06_g2217	A4X06_g6172	A0A177VSZ0	A0A177UZE3	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.625
A4X06_g2217	A4X06_g7360	A0A177VSZ0	A0A177U6T2	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.900
A4X06_g2217	A4X06_g7736	A0A177VSZ0	A0A177U3W0	Ubiquitin-like domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.778
A4X06_g2218	A4X06_g1660	A0A177VSK2	A0A177VUC0	Uncharacterized protein.	RING-type domain-containing protein.	0.849
A4X06_g2218	A4X06_g2336	A0A177VSK2	A0A177VSB7	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.778

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070006

Metalloaminopeptidase activity

4 of 9

2.41

2.88

3.04e-06

GO:0030145

Manganese ion binding

3 of 9

2.29

2.03

0.00013

GO:0046914

Transition metal ion binding

5 of 110

1.42

1.46

0.00013

GO:0046872

Metal ion binding

8 of 627

0.87

0.8

0.00013

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005965

Protein farnesyltransferase complex

2 of 3

2.59

1.03

0.0132

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8231

Mixed, incl. Pyrimidine nucleotide-sugar transmembrane transport, and Macromolecule depalmitoylation

6 of 35

2.0

3.43

2.02e-08

CL:8236

Pyrimidine nucleotide-sugar transmembrane transport, and Aminopeptidase activity

5 of 21

2.14

3.34

1.05e-07

CL:6054

Terpenoid backbone biosynthesis, and Short chain dehydrogenase

4 of 22

2.02

2.37

1.31e-05

CL:8258

Pyrimidine nucleotide-sugar transmembrane transport, and Aminopeptidase P, N-terminal

3 of 10

2.24

1.96

0.00017

CL:8260

Nucleotide-sugar transporter, and Aminopeptidase P, N-terminal

2 of 5

2.37

1.18

0.0066

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

4 of 20

2.06

2.55

5.82e-06

map00260

Glycine, serine and threonine metabolism

4 of 20

2.06

2.55

5.82e-06

map01100

Metabolic pathways

8 of 959

0.68

0.55

0.0011

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005965

Protein farnesyltransferase complex

2 of 3

2.59

0.99

0.0156

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0464

Manganese

3 of 12

2.16

1.81

0.00031

KW-0031

Aminopeptidase

2 of 11

2.02

0.93

0.0172

KW-0479

Metal-binding

5 of 353

0.91

0.58

0.0172

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00557

Metallopeptidase family M24

4 of 10

2.37

2.81

3.81e-06

PF00432

Prenyltransferase and squalene oxidase repeat

2 of 3

2.59

1.08

0.0108

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029149

Creatinase/Aminopeptidase P/Spt16, N-terminal

4 of 5

2.67

3.13

1.48e-06

IPR036005

Creatinase/aminopeptidase-like

4 of 10

2.37

2.72

5.86e-06

IPR000994

Peptidase M24

4 of 10

2.37

2.72

5.86e-06

IPR007865

Aminopeptidase P, N-terminal

3 of 3

2.76

2.36

4.70e-05

IPR045089

Prenyltransferase subunit beta

2 of 3

2.59

1.03

0.0133

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01011

Aminopeptidase P, N-terminal domain

3 of 3

2.76

2.55

2.05e-05

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