A4X06_g4763 protein (Tilletia controversa) - STRING interaction network

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Score

A4X06_g4763

Integrase catalytic domain-containing protein. (482 aa)

Predicted Functional Partners:

A4X06_g5868

0.604

A4X06_g4024

0.604

A4X06_g5986

0.597

A4X06_g4802

0.597

A4X06_g7396

0.564

A4X06_g7158

0.564

A4X06_g4032

0.564

A4X06_g144

0.564

A4X06_g4056

0.560

A4X06_g172

0.560

Your Current Organism:

Tilletia controversa

NCBI taxonomy Id: 13291
Other names: T. controversa, Tilletia contraversa, dwarf bunt fungus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4X06_g144	A4X06_g4032	A0A177VXN9	A0A177VNU0	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.998
A4X06_g144	A4X06_g4763	A0A177VXN9	A0A177VJ58	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Integrase catalytic domain-containing protein.	0.564
A4X06_g144	A4X06_g7158	A0A177VXN9	A0A177U9F0	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
A4X06_g144	A4X06_g7396	A0A177VXN9	A0A177U729	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
A4X06_g172	A4X06_g4056	A0A177VZF5	A0A177VNK5	Uncharacterized protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.982
A4X06_g172	A4X06_g4763	A0A177VZF5	A0A177VJ58	Uncharacterized protein.	Integrase catalytic domain-containing protein.	0.560
A4X06_g172	A4X06_g4802	A0A177VZF5	A0A177VKI1	Uncharacterized protein.	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family.	0.946
A4X06_g172	A4X06_g5986	A0A177VZF5	A0A177V8J5	Uncharacterized protein.	Cytochrome b5 heme-binding domain-containing protein.	0.946
A4X06_g4024	A4X06_g4763	A0A177VNP3	A0A177VJ58	Lysophospholipase.	Integrase catalytic domain-containing protein.	0.604
A4X06_g4024	A4X06_g5868	A0A177VNP3	A0A177V830	Lysophospholipase.	Lysophospholipase.	0.831
A4X06_g4032	A4X06_g144	A0A177VNU0	A0A177VXN9	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
A4X06_g4032	A4X06_g4763	A0A177VNU0	A0A177VJ58	Uncharacterized protein.	Integrase catalytic domain-containing protein.	0.564
A4X06_g4032	A4X06_g7158	A0A177VNU0	A0A177U9F0	Uncharacterized protein.	Uncharacterized protein.	0.998
A4X06_g4032	A4X06_g7396	A0A177VNU0	A0A177U729	Uncharacterized protein.	Uncharacterized protein.	0.998
A4X06_g4056	A4X06_g172	A0A177VNK5	A0A177VZF5	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Uncharacterized protein.	0.982
A4X06_g4056	A4X06_g4763	A0A177VNK5	A0A177VJ58	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Integrase catalytic domain-containing protein.	0.560
A4X06_g4056	A4X06_g4802	A0A177VNK5	A0A177VKI1	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family.	0.946
A4X06_g4056	A4X06_g5986	A0A177VNK5	A0A177V8J5	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Cytochrome b5 heme-binding domain-containing protein.	0.946
A4X06_g4763	A4X06_g144	A0A177VJ58	A0A177VXN9	Integrase catalytic domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.564
A4X06_g4763	A4X06_g172	A0A177VJ58	A0A177VZF5	Integrase catalytic domain-containing protein.	Uncharacterized protein.	0.560

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Network Stats

number of nodes:

11

number of edges:

19

average node degree:

3.45

avg. local clustering coefficient:

0.839

expected number of edges:

10

PPI enrichment p-value:

0.0107

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 363

1.81

4.51

1.52e-14

GO:0000028

Ribosomal small subunit assembly

3 of 14

2.7

2.75

7.98e-06

GO:0032543

Mitochondrial translation

2 of 64

1.86

0.73

0.0410

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 183

2.06

5.64

5.65e-15

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005763

Mitochondrial small ribosomal subunit

8 of 27

2.84

9.32

7.04e-19

GO:0005761

Mitochondrial ribosome

9 of 70

2.47

8.45

7.04e-19

GO:0044391

Ribosomal subunit

9 of 159

2.12

6.34

1.37e-16

GO:0098798

Mitochondrial protein-containing complex

9 of 226

1.97

5.39

1.99e-15

GO:0005739

Mitochondrion

10 of 1053

1.34

2.32

1.18e-11

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:10972

Organellar ribosome, and Ribosomal large subunit binding

10 of 105

2.34

8.33

6.93e-20

CL:11006

Organellar ribosome

6 of 33

2.63

6.01

1.79e-12

CL:11040

Organellar small ribosomal subunit

5 of 16

2.86

5.62

2.85e-11

CL:11142

Organellar small ribosomal subunit, and JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1

4 of 15

2.79

4.24

1.24e-08

CL:11146

Organellar small ribosomal subunit, and PEBP-like superfamily

3 of 10

2.84

3.04

2.59e-06

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

8 of 217

1.93

4.61

8.02e-13

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

6 of 343

1.61

2.15

2.55e-06

MAP-392499

Metabolism of proteins

6 of 1723

0.91

0.58

0.0154

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005763

Mitochondrial small ribosomal subunit

8 of 33

2.75

9.06

1.17e-18

GOCC:0005761

Mitochondrial ribosome

9 of 71

2.47

8.37

9.98e-19

GOCC:0044391

Ribosomal subunit

9 of 175

2.08

6.06

3.33e-16

GOCC:0098798

Mitochondrial protein complex

9 of 184

2.05

5.93

4.52e-16

GOCC:0005739

Mitochondrion

10 of 788

1.47

2.87

8.98e-13

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 107

2.04

3.15

1.59e-07

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