STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKI96873.1DNA integrity scanning protein DisA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DisA family. (355 aa)    
Predicted Functional Partners:
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.922
AKI96871.1
Clp protease ClpX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
  
    0.810
AKI98214.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.736
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.736
AKI96869.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.654
AKI97152.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.487
AKI96712.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.477
AKI96839.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.424
Your Current Organism:
Kosmotoga pacifica
NCBI taxonomy Id: 1330330
Other names: DSM 26965, JCM 19180, K. pacifica, Kosmotoga sp. SLHLJ1, MCCC 1A00641, UBOCC 3254, strain SLHLJ1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.